14 mins read

Does SRSF1 Reverse Ageing? One Gene, Real Cells, Zero Human Proof

Does SRSF1 reverse ageing? In old human cells in a dish and in aged mice, boosting this one gene shifted cells toward a younger state and extended median lifespan by 14%. In people, it has not been tested at all. That gap, between a striking laboratory result and any human evidence, is the whole story […]

12 mins read

Does Urolithin A Actually Do Anything for Muscle?

Does urolithin A work? If you have seen the $99 strawberry gummies promising to change how your cells age, that is the question to ask before you subscribe. Urolithin A is a postbiotic compound your gut can make from pomegranate, berries and walnuts, and the supplement industry’s pitch rests on one striking number: a randomised […]

15 mins read

Can You Train Processing Speed, the Brain Skill Tied to Longer Life?

Short answer: Yes, probably. In a study of 4,561 Australian adults followed for a median of 11.3 years, each standard-deviation increase in processing speed was linked to 32% lower mortality (hazard ratio 0.68), after adjusting for education, lifestyle and health factors. And in the ACTIVE trial of about 2,800 older adults, ten hours of adaptive […]

12 mins read

How Often Should You Cold Plunge? The Protocol That Makes Sense

Short answer: No randomised trial has ever established an optimal weekly cold plunge frequency. The best-supported approach from the current evidence is 2 to 4 sessions per week, totalling roughly 11 minutes of immersion at 10 to 15°C, with the dose of each session mattering far more than how often you get in. If you […]

17 mins read

What 6 Habits Are Aging You Faster? (And What to Do Instead)

What 6 Habits Are Aging You Faster? What 6 habits are aging you faster? Smoking, sitting all day, sleeping under 6 hours, drinking heavily, living on ultra-processed food and chronic loneliness. Researchers can now estimate how fast your body is aging by reading chemical marks on your DNA, known as epigenetic clocks, and all six […]

12 mins read

What Are the Top 3 Supplements for Longevity? What Research Actually Supports

The short answer What are the top 3 supplements for longevity? Ranked strictly by human evidence on ageing-relevant outcomes, they are: omega-3 fatty acids (1 g a day, the only supplement with trial evidence of slowed biological ageing), vitamin D3 (2,000 IU a day, strongest as part of a three-part stack that cut invasive cancer […]

18 mins read

What Increases Lifespan the Most? Ranked by the Evidence.

Ask ten longevity enthusiasts what increases lifespan the most and you will get ten different answers: metformin, rapamycin, cold plunges, NAD boosters, fasting. The published evidence gives a much less exciting, much more useful answer. The single biggest lever ever measured in humans is quitting smoking, worth about a decade of life. Stack five ordinary […]

12 mins read

Can You Gain Muscle From Creatine Without Exercise? What the 12-Week Trial Found

Creatine without exercise sounds like a contradiction. For decades the default advice has been that creatine only pays off when paired with hard training. A new 12-week trial from Texas A&M University, published in the Journal of the International Society of Sports Nutrition in 2026, tested that assumption directly: sedentary but healthy adults aged 45 […]